AG-1749 Lansoprazole

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Chemical Information

Product name：AG-1749 Lansoprazole	Purity：98% min
CAS NO：103577-45-3	Solubility：DMSO : 100 mg/mL (270.74 mM)
Molecular Formula：C₁₆H₁₄F₃N₃O₂S	Package：Package according to customer requirements
Molecular Weight：369.361	Storage：Store at 2-8ºC

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Remarks

Lansoprazole is a proton-pump inhibitor (PPI) in the same pharmacologic class as omeprazole which inhibits the stomach's production of gastric acids. As of 2015, laboratory studies were underway on analogs of lansoprazole to explore their use as potential PET imaging agents for diagnosing tauopathies including Alzheimer's disease. Lansoprazole is also a prodrug that targets the cytochrome bc1 complex of Mycobacterium tuberculosis once converted to lansoprazole sulfide in mycobacterial host cells.

Properties:
Appearance & Physical State: White Crystalline Powder
Density: 1.5 g/cm3
Melting Point: 178-182ºC
Boiling Point: 555.8ºC at 760 mmHg
Flash Point: 289.9ºC
Refractive Index: 1.591
Vapor Pressure: 2.55E-10mmHg at 25°C

Proton Pump Inhibitors Related Products:

PF-03716556; Dexlansoprazole; Rebeprazole sodium; Bafilomycin A1

References

[1]. Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5.

[2]. Lai, K.C., et al., Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med, 2002. 346(26): p. 2033-8.