Cefditoren

Cefditoren, is a cephalosporin antibiotic potentially for the treatment of bacterial infection. The expression levels of Mrp2, Bcrp, Oat2 mRNA were markedly increased, while P-gp and Oct1 mRNA were decreased. In concordance with RT-PCR results, Mrp2 expression level increased by Western blotting. These results indicate that Mrp2 and Bcrp may be involved in the biliary excretion of cefditoren. Cefditoren can up-regulate the expression levels of Mrp2, Bcrp and Oat2, and down-regulate P-gp and Oct1 mRNA expression.

Properties:
Density 1.75g/cm3
Refractive Index 1.825

Bacterial inhibitor Related Products:

Pretomanid; Pyrazinamide; Sulfanilamide; Walrycin B; Daptomycin; Tigecycline; Rifabutin; Biapenem; Teicoplanin; Cefditoren Pivoxil; Cefdinir; Azithromycin; Trimethoprim; Vancomycin HCl; Amoxicillin; Dalbavancin; Cefoxitin acid; Ceftibuten dihydrate; Besifloxacin; Solithromycin; Dalbavancin HCl; Cefoxitin Sodium; Besifloxacin Hydrochloride; Pleuromutilin

1: Sadahira T, Wada K, Araki M, Ishii A, Takamoto A, Kobayashi Y, Watanabe M, Watanabe T, Nasu Y, Kumon H; Okayama Urological Research Group (OURG).. Efficacy and safety of 3 day versus 7 day cefditoren pivoxil regimens for acute uncomplicated cystitis: multicentre, randomized, open-label trial. J Antimicrob Chemother. 2017 Feb;72(2):529-534. doi: 10.1093/jac/dkw424. PubMed PMID: 27733519.

2: Ulloa C, Guevara S, Soley C, Abdelnour A, Arguedas A. In vitro Activity of Cefditoren against Middle Ear Fluid Isolates from Costa Rican Children with Otitis Media. Chemotherapy. 2014;60(4):211-8. doi: 10.1159/000371836. PubMed PMID: 25871785.