Temocapril hydrochloride

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Chemical Information

Product name：Temocapril hydrochloride	Purity：98% min
CAS NO：110221-44-8	Solubility：DMSO : ≥ 100 mg/mL (194.91 mM)
Molecular Formula：C₃₅H₄₄N₂O₁₀	Package：Package according to customer requirements
Molecular Weight：652.731	Storage：Store at -20℃

Quality control

Remarks

Temocapril Hydrochloride is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. Target: ACE Temocapril hydrochloride is a novel prodrug-type angiotensin-I converting enzyme (ACE) inhibitor, lowering of the dose of temocapril might be recommended only in patients with severe renal insufficiency .Temocapril is regarded as an ACE inhibitor the disposition and efficacy of which are little affected in patients with impaired liver function.

RAAS Inhibitors Related Prodcuts:

Azilsartan; VTP-27999 TFA; Eprosartan Mesylate; Telmisartan; Valsartan; Enalapril Maleate; Sparsentan; Fimasartan; Fosinopril Sodium; Olmesartan medoxomil

References

[1]. Nakashima, M., et al., Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency. Eur J Clin Pharmacol, 1992. 43(6): p. 657-9.

[2]. Furuta, S., et al., Pharmacokinetics of temocapril, an ACE inhibitor with preferential biliary excretion, in patients with impaired liver function. Eur J Clin Pharmacol, 1993. 44(4): p. 383-5.