TAK-536 Azilsartan

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Chemical Information

Product name：TAK-536 Azilsartan	Purity：98% min
CAS NO：147403-03-0	Solubility：DMSO : 25 mg/mL (54.77 mM)
Molecular Formula：C₂₅H₂₀N₄O₅	Package：Package according to customer requirements
Molecular Weight：456.45	Storage：Store at -20℃

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Remarks

Azilsartan is an angiotensin II receptor antagonist used in the treatment of hypertension, developed by Takeda. It is marketed in tablet form under the trade name Edarbi as the prodrug azilsartan medoxomil (INN, codenamed TAK-491). Azilsartan medoxomil lowers blood pressure by blocking the action of angiotensin II, a vasopressor hormone.

RAAS Inhibitors Related Prodcuts:

Aliskiren hemifumarate; Candesartan; Candesartan Cilexetil; Losartan potassium; Enalaprilat dihydrate; Irbesartan; PD123319; Perindopril Erbumine; Ramipril; Captopril; VTP-27999 TFA; Eprosartan Mesylate; Telmisartan; Valsartan; Enalapril Maleate ; Benazepril

References

[1]. Ojima M, Igata H, Tanaka M, In vitro antagonistic properties of a new angiotensin type 1 receptor blocker, azilsartan, in receptor binding and function studies. J Pharmacol Exp Ther. 2011 Mar;336(3):801-8.

[2]. Weltman R, Brands CM, Corral E, Assessment of the environmental fate and effects of azilsartan, a selective antagonist of angiotensin II type 1. Chemosphere. 2012 Jun;87(11):1323-9.