Perindopril erbumine

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Chemical Information

Product name：Perindopril erbumine	Purity：98% min
CAS NO：107133-36-8	Solubility：DMSO : 10 mg/mL (22.64 mM)
Molecular Formula：C₂₃H₄₃N₃O₅	Package：Package according to customer requirements.
Molecular Weight：441.605	Storage：-20ºC

Quality control

Remarks

Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research.

Properties:

Appearance & Physical State: white solid

Density: 1.15 g/cm3

Boiling Point: 537.4ºC at 760mmHg

Melting Point: 126-128ºC

Flash Point: 278.8ºC

RAAS Inhibitors Related Prodcuts:

Aliskiren hemifumarate; Candesartan; Candesartan Cilexetil; Losartan potassium; Enalaprilat dihydrate; Irbesartan; PD123319; Ramipril; Captopril; Azilsartan; VTP-27999 TFA; Eprosartan Mesylate; Telmisartan; Valsartan; Enalapril Maleate ; Benazepril

References

[1]. Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4.

[2]. Napalkov DA. Therapy with perindopril: organoprotection, not just the antihypertensive effect. Kardiologiia. 2012;52(12):80-3.