Welcome to Crene Biotechnology!

+86-576-88205808

Product :

ELR510444

ELR510444 1233948-35-0
Size Price Stock Quantity
Get Quotation Now Add to Cart Bulk Inquiry
Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Chemical Information
Product name:ELR510444 Purity:98% min
CAS NO:1233948-35-0 Solubility:DMSO : ≥ 37 mg/mL (100.42 mM)
Molecular Formula:C19H16N2O2S2 Package:Package according to customer requirements
Molecular Weight:368.473 Storage:Store at -20℃
Quality control
Remarks
ELR510444 is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30.9 nM in MDA-MB-231 cells, inhibited the rate and extent of purified tubulin assembly, and displaced colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Friendly link:

Copyright Copyright (C) 2018-2021Taizhou Crene Biotechnology Co., Ltd.

Address:Economic Developed Zone of Taizhou Zhejiang China.