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Tucidinostat Chidamide impurity

Tucidinostat Chidamide impurity 743420-02-2
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Chemical Information
Product name:Tucidinostat Chidamide impurity Purity:98% min
CAS NO:743420-02-2 Solubility:DMSO : ≥ 41 mg/mL (105.02 mM)
Molecular Formula:C22H19FN4O2 Package:Package according to customer requirements
Molecular Weight:390.41 Storage:Store at -20℃
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Chidamide, also known as Tucidinostat , CS055 and HBI-8000 , is a n orally bioavailable benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with potential antineoplastic activity. Chidamide selectively binds to and inhibits HDAC leading to an increase of acetylation levels of histone protein H3. This agent also inhibits the expression of signaling kinases in the PI3K/Akt and MAPK/Ras signaling pathways and may result in cell cycle arrest and the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells.
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