Isocyclosporin A

Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.

Properties:
Density: 1.19g/cm3
Refractive Index: 1.571

Related Products:  

Dihydrocyclosporin D; Dihydrocyclosporin C; Dihydrocyclosporin A; Cyclosporin H; Cyclosporin D; Cyclosporin C; Cyclosporin B; Cyclosporin A

1: Sanglier JJ, Traber R, Buck RH, Hofmann H, Kobel H. Isolation of (4R)-4-[(E)-2-butenyl]-4-methyl-L-threonine, the characteristic structural element of cyclosporins, from a blocked mutant of Tolypocladium inflatum. J Antibiot (Tokyo). 1990 Jun;43(6):707-14. PubMed PMID: 2116402.

2: Meier GP, Park SB, Yee GC, Gmur DJ. Isolation and identification of a novel human metabolite of cyclosporin A: dihydro-CsA M17. Drug Metab Dispos. 1990 Jan-Feb;18(1):68-71. PubMed PMID: 1970780.