Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts.
Related Products:
Dihydrocyclosporin D; Dihydrocyclosporin C; Dihydrocyclosporin A; Cyclosporin H; Cyclosporin D; Cyclosporin C; Cyclosporin A; Isocyclosporin A