Cyclosporin C

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Chemical Information

Product name：Cyclosporin C	Purity：98% min
CAS NO：59787-61-0	Solubility：Soluble in DMSO
Molecular Formula：C₆₂H₁₁₁N₁₁O₁₃	Package：Package according to customer requirements
Molecular Weight：1218.610	Storage：Store at -20℃

Quality control

Remarks

Cyclosporin C is a broad-spectrum antifungal agent against filamentous phytopathogenic fungi but no activity against bacteria or yeasts.

Properties
Appearance & Physical State: Colorless to off-white crystalline solid.
Density: 1.033 g/cm3
Melting Point: 152-155ºC
Boiling Point: 1316ºC at 760 mmHg
Flash Point: 749.7ºC
Refractive Index: 1.472

Related Products:

Dihydrocyclosporin D; Dihydrocyclosporin C; Dihydrocyclosporin A; Cyclosporin H; Cyclosporin D; Cyclosporin B; Cyclosporin A ; Isocyclosporin A

References

1: Xu L, Li Y, Biggins JB, Bowman BR, Verdine GL, Gloer JB, Alspaugh JA, Bills GF. Identification of cyclosporin C from Amphichorda felina using a Cryptococcus neoformans differential temperature sensitivity assay. Appl Microbiol Biotechnol. 2018 Mar;102(5):2337-2350. doi: 10.1007/s00253-018-8792-0. Epub 2018 Feb 2. PubMed PMID: 29396588.

2: Iijima K, Sako M, Oba MS, Ito S, Hataya H, Tanaka R, Ohwada Y, Kamei K, Ishikura K, Yata N, Nozu K, Honda M, Nakamura H, Nagata M, Ohashi Y, Nakanishi K, Yoshikawa N; Japanese Study Group of Kidney Disease in Children. Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: a multicenter randomized phase II trial. Clin J Am Soc Nephrol. 2014 Feb;9(2):271-8. doi: 10.2215/CJN.13071212. Epub 2013 Nov 21. PubMed PMID: 24262503; PubMed Central PMCID: PMC3913253.