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SCR7 1533426-72-0
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Chemical Information
Product name:SCR7 Purity:98% min
CAS NO:1533426-72-0 Solubility:DMSO : ≥ 45 mg/mL (134.57 mM)
Molecular Formula:C18H14N4OS Package:Package according to customer requirements
Molecular Weight:334.395 Storage:Store at -20℃
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SCR7 is a specific DNA Ligase IV inhibitor. SCR7 inhibits end joining of double strand breaks in diverse cell types resulting in tumour regression by activation of p53 mediated apoptosis. Notably SCR7 treatment did not result in any adverse effects in mice and did not inhibit Ligase III. The therapeutic efficacy of SCR7 could be enhanced by specific delivery of SCR7 to the tumour tissue and as adjuvant cancer therapy. SCR7 appears to be a potential cytotoxic anti-cancer drug candidate that can be used either alone or in combination with conventional DNA damaging drugs, owing to its specificity and absence of adverse effects in mice model.




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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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