Benzamidine hydrochloride

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Chemical Information

Product name：Benzamidine hydrochloride	Purity：98% min
CAS NO：1670-14-0	Solubility：DMSO : 100 mg/mL (638.53 mM)
Molecular Formula：C₇H₉ClN₂	Package：Package according to customer requirements.
Molecular Weight：156.613	Storage：-20ºC

Quality control

Remarks

Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively.

Synonyms:

BENZAMIDE HCL H2O;

phenyl amidine hydrochloride;

benzenecarboximidamide hydrochloride;

benzamidine hydroxychloride;

benzamidinium chloride;

Benzenecarboximidamide monohydrochloride;

Properties:

Appearance & Physical State: white to off-white powder

Density: 1.09 g/cm3

Boiling Point: 332.9ºC at 760 mmHg

Melting Point: 167-171ºC

Flash Point: 155.1ºC

Vapor Pressure: 5.63E-05mmHg at 25°C

Serine/threonin kinase Inhibitors Related Products:

BAY-1816032; SP600125; Ceritinib; SRPIN340; SGC-GAK-1; WNK463; Benzamidine

References

[1]. Tanizawa K, et al. Proteolytic enzymes. VI. Aromatic amidines as competitive inhibitors of trypsin. J Biochem. 1971 May;69(5):893-9.

[2]. Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7(4):299-312.