Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.
It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.
Synonyms:
Benzamidinium chloride;
Benzenecarboximidamide;
phenyl-amidine;
benzimidamide;
Properties:
Density: 1.09 g/cm3
Boiling Point: 208.5ºC at 760 mmHg
Melting Point: 65-70ºC
Flash Point: 79.9ºC
Serine/threonin kinase Inhibitors Related Products:
BAY-1816032; SP600125; Ceritinib; SRPIN340; Benzamidine hydrochloride; SGC-GAK-1; WNK463