Darunavir

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Chemical Information

Product name：Darunavir	Purity：98% min
CAS NO：206361-99-1	Solubility：DMSO : ≥ 100 mg/mL (182.60 mM)
Molecular Formula：C₂₇H₃₇N₃O₇S	Package：Package according to customer requirements
Molecular Weight：547.664	Storage：Store at -20℃

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Remarks

Darunavir (formerly known as TMC114) is a protease inhibitor medication used to treat HIV infection. Darunavir is an OARAC recommended treatment option for treatment-naïve and treatment-experienced adults and adolescents.

Properties:
Appearance & Physical State: White Amorphous Solid
Density: 1.34g/cm3
Melting Point: 74-76ºC
Refractive Index: 1.62

HIV Protease Inhibitors Related Prodcuts:

Lopinavir; Atazanavir; Panobinostat; Temsavir; Darunavir; Pepstatin A

References

[1]. Ghosh AK, et al. Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV. Bioorg Med Chem. 2007 Dec 15;15(24):7576-80.

[2]. Dierynck I, et al. Binding kinetics of darunavir to human immunodeficiency virus type 1 protease explain the potent antiviral activity and high genetic barrier. J Virol. 2007 Dec;81(24):13845-51. Epub 2007 Oct 10.