Pepstatin is a specific aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease.
Properties:
Appearance & Physical State: solid
Density: 1.117 g/cm3
Boiling Point: 997.6ºC at 760 mmHg
Melting Point: 233ºC (dec.)(lit.)
Flash Point: 557.1ºC
Refractive Index: 1.504
Cysteine Protease Inhibitors Related Prodcuts:
Odanacatib; E-64; PMSF; Balicatib; Leupeptin hemisulfate; Aloxistatin