PMSF Benzylsulfonyl fluoride

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Chemical Information

Product name：PMSF Benzylsulfonyl fluoride	Purity：99% min
CAS NO：329-98-6	Solubility：DMSO : 20 mg/mL (114.82 mM)
Molecular Formula：C₇H₇FO₂S	Package：Packaging according to customer requirements
Molecular Weight：174.193	Storage：2-8ºC

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Remarks

PMSF is an inhibitor of serine proteases such as trypsin and chymotrypsin. It also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase.

Properties:
Appearance & Physical State: White to cream solid
Density: 1.317 g/cm3
Boiling Point: 285.7ºC at 760 mmHg
Melting Point: 90-94ºC
Flash Point: 126.6ºC
Refractive Index: 1.502

Cysteine Protease Inhibitors Related Prodcuts:

Odanacatib; E-64; Balicatib; Pepstatin A; Leupeptin hemisulfate ; Aloxistatin

References

[1]. Sekar, M.C. and B.D. Roufogalis, Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum. Cell Calcium, 1984. 5(3): p.

[2]. Guther, M.L., W.J. Masterson, and M.A. Ferguson, The effects of phenylmethylsulfonyl fluoride on inositol-acylation and fatty acid remodeling in African trypanosomes. J Biol Chem, 1994. 269(28): p. 18694-701.