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Product :

LY-411575

LY-411575 209984-57-6
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Chemical Information
Product name:LY-411575 Purity:98% min
CAS NO:209984-57-6 Solubility:DMSO : 33.33 mg/mL (69.51 mM)
Molecular Formula:C26H23F2N3O4 Package:Package according to customer requirements
Molecular Weight:479.475 Storage:Store at -20℃
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Remarks

LY 411575, also known as LSN-411575, is potent, cell permeable and selective γ-secretase inhibitor that reduces Aβ/42 after acute or chronic treatment, and blocks Notch activation. The gamma secretase inhibitor, activating pPKC alpha intracellular pathway could be suggested to prevent or reduce downstream toxic events, representing a useful strategy to counteract Alzheimer's disease.

 

 

 

Gamma-secretase Inhibitors Related Products:

RO4929097; Semagacestat; Avagacestat; Dibenzazepine; Crenigacestat; DAPT (GSI-IX)

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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