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Levobupivacaine

Levobupivacaine 27262-47-1
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Chemical Information
Product name:Levobupivacaine Purity:98% min
CAS NO:27262-47-1 Solubility:Soluble in DMSO
Molecular Formula:C18H29ClN2O Package:Package according to customer requirements
Molecular Weight:324.889 Storage:Store at -20℃
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Remarks

Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children. Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time.

 

 

 

Sodium Channel Inhibitors Related Products:  

Carbamazepine; A-803467; Camostat Mesilate; Ambroxol hcl; Proparacaine hydrochloride; Rufinamide; Zonisamide; Zonisamide sodium salt; Dronedarone hcl; Baricitinib; Levobupivacaine hcl; Vinpocetine; Propafenone hcl; Lamotrigine

References

1: Lv BS, Wang W, Wang ZQ, Wang XW, Wang JH, Fang F, Mi WD. Efficacy and safety of local anesthetics bupivacaine, ropivacaine and levobupivacaine in combination with sufentanil in epidural anesthesia for labor and delivery: a meta-analysis. Curr Med Res Opin. 2014 Nov;30(11):2279-89. doi: 10.1185/03007995.2014.946127. Epub 2014 Aug 5. Review. PubMed PMID: 25050590.

2: Sanford M, Keating GM. Levobupivacaine: a review of its use in regional anaesthesia and pain management. Drugs. 2010 Apr 16;70(6):761-91. doi: 10.2165/11203250-000000000-00000. Review. PubMed PMID: 20394458.

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