Vinpocetine, also known as AY-27,255 and RGH-4405, is a synthetic derivative of the vinca alkaloid vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"), an extract from the lesser periwinkle plant. Vinpocetine has been reported to have cerebral blood-flow enhancing and neuroprotective effects, and has been used as a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment. Vinpocetine acts as a phosphodiesterase (PDE) type-1 inhibitor in isolated rabbit aorta, Independent of vinpocetine's action on PDE, vinpocetine inhibits IKK preventing IκB degradation and the following translocation of NF-κB to the cell nucleus.
Sodium Channel Inhibitors Related Products:
Carbamazepine; A-803467; Camostat Mesilate; Ambroxol hcl; Proparacaine hydrochloride; Rufinamide; Zonisamide; Zonisamide sodium salt; Dronedarone hcl; Baricitinib; Levobupivacaine; Levobupivacaine hcl; Propafenone hcl; Lamotrigine