Scriptaid

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Chemical Information

Product name：Scriptaid	Purity：98% min
CAS NO：287383-59-9	Solubility：DMSO : ≥ 150 mg/mL (459.63 mM)
Molecular Formula：C₁₈H₁₈N₂O₄	Package：Package according to customer requirements
Molecular Weight：326.347	Storage：Store at -20℃

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Remarks

Scriptaid, also known as GCK 1026, is a HDAC inhibitor. Scriptaid protects against traumatic brain injury via modulation of PTEN and AKT pathway. Scriptaid improves in vitro development and nuclear reprogramming of somatic cell nuclear transfer bovine embryos. Scriptaid enhances the response of human tumor cells to radiation. Scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity.

Related Prodcuts:

Talazoparib; Aleglitazar; Miriplatin; Ceritinib; CGK733; Tacedinaline; P005091; PR-619; Gemcitabine; Gemcitabine HCL; Terbinafine hydrochloride; Mitomycin C; Clevudine;Givinostat hydrochloride monohydrate

References

[1]. Keen JC, et al. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. Breast Cancer Res Treat. 2003 Oct;81(3):177-86.

[2]. Strobl JS, et al. Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. J Parasitol. 2007 Jun;93(3):694-700.