Terbinafine HCl is a synthetic allylamine antifungal, is used topically for skin infections. Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.
Properties:
Appearance & Physical State: Crystalline powder
Density: 1.007g/cm3
Melting Point: 204-208ºC
Boiling Point: 417.9ºC at 760 mmHg
Flash Point: 183.7ºC
Refractive Index: 1.586
Storage Condition: -20ºC Freezer
Related Prodcuts:
Talazoparib; Aleglitazar; Miriplatin; Scriptaid; Ceritinib; CGK733; Tacedinaline; P005091; PR-619; Gemcitabine; Gemcitabine HCL; Mitomycin C; Clevudine; Givinostat hydrochloride monohydrate