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Gemcitabine hydrochloride

Gemcitabine hydrochloride 122111-03-9
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Chemical Information
Product name:Gemcitabine hydrochloride Purity:99%min
CAS NO:122111-03-9 Solubility:Soluble in DMSO
Molecular Formula:C9H11F2N3O4.HCl Package:Packaging according to customer requirements
Molecular Weight:299.66 Storage:Store at -20℃
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Remarks
Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Treatment of BxPC-3 cells with low dose Gemcitabine for 48 hours results in a dose-dependent increase in NF-κB binding. In contrast, NF-κB DNA binding is decreased in BxPC-3 cells treated with the higher Gemcitabine doses for 48 h; however, 24-h treatment with these higher doses increases NF-κB binding in BxPC-3 cells
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