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Product :

Cladribine

Cladribine 4291-63-8
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Chemical Information
Product name:Cladribine Purity:98% min
CAS NO:4291-63-8 Solubility:DMSO : ≥ 30 mg/mL (105.01 mM)
Molecular Formula:C10H12ClN5O3 Package:Packaging according to customer requirements
Molecular Weight:285.69 Storage:Store at 2-8ºC
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Remarks

Cladribine is a purine nucleoside antimetabolite analogue. Cladribine triphosphate, a phosphorylated metabolite of cladribine, incorporates into DNA, resulting in single-strand breaks in DNA, depletion of nicotinamide adenine dinucleotide (NAD) and adenosine triphosphate (ATP), and apoptosis. Because this agent is resistant to adenosine deaminase, an enzyme that inactivates some antineoplastic agents, it is selectively toxic to lymphocytes and monocytes which exhibit little deoxynucleotide deaminase activity.

 

Properties:

Appearance & Physical State: White Crystalline Solid

Density: 2.03g/cm3

Boiling Point: 547.6ºC at 760 mmHg

Melting Point: 181-185ºC(lit.)

Flash Point: 285ºC

 

 

 

Related Prodcuts: 

Cisplatin; Gemcitabine HCL; Bleomycin Sulfate; Temozolomide; Carmustine; CX-5461; Fludarabine Phosphate; Nelarabine; Trifluridine; Daptomycin

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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