Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a medication used mainly for chemotherapy and sometimes for immunosuppression before organ transplantation. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent. As a dialkylating agent, BCNU is able to form interstrand crosslinks in DNA, which prevents DNA replication and DNA transcription.
It has the appearance of an orange-yellow solid.
Carmustine for injection was earlier marketed under the name BiCNU by Bristol-Myers Squibb and now by Emcure Pharmaceuticals. In India it is sold under various brand names, including Consium.
Properties:
Appearance & Physical State: Orange-yellow solid.
Density: 1.46 g/ml
Boiling Point: 404ºC
Melting Point: 30ºC
Refractive Index: 1.548
Related Prodcuts:
Cisplatin; Gemcitabine HCL; Bleomycin Sulfate; Temozolomide; CX-5461; Fludarabine Phosphate; Nelarabine; Cladribine; Trifluridine; Daptomycin