JTE-013 is a potent, selective sphingosine-1-phosphate 2 (S1P2) receptor antagonist that binds to the human and rat receptors with IC50 values of 17 and 22 nM, respectively, (IC50 values >10 µM for human S1P1 and S1P3).
Synonyms:
JTE-013;
HMS3269A03;
S1P2 Receptor Antagonist,JTE-013;
pyrazolopyridine analog;
S1P Receptor Inhibitors Related Products:
Fingolimod hydrochloride; Ponesimod; Ozanimod