Welcome to Crene Biotechnology!

+86-576-88205808

Product :

Ponesimod ACT-128800

Ponesimod ACT-128800 854107-55-4
Size Price Stock Quantity
Get Quotation Now Add to Cart Bulk Inquiry
Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Chemical Information
Product name:Ponesimod ACT-128800 Purity:99% min
CAS NO:854107-55-4 Solubility:DMSO : ≥ 100 mg/mL (216.93 mM)
Molecular Formula:C23H25ClN2O4S Package:Package according to customer requirements
Molecular Weight:99% min Storage:Store at -20℃
Quality control
Remarks

Ponesimod, also known as ACT-128800, is a potent, and orally active selective S1P(1) agonist. Ponesimod activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity. Ponesimod prevented edema formation, inflammatory cell accumulation, and cytokine release in the skin of mice with delayed-type hypersensitivity. Ponesimod also prevented the increase in paw volume and joint inflammation in rats with adjuvant-induced arthritis. Ponesimod may represent a new therapeutic approach in lymphocyte-mediated autoimmune diseases.

 

Properties:

Boiling point: 658.0±65.0 °C(Predicted)

density: 1.30±0.1 g/cm3(Predicted)

pka: 13.38±0.20(Predicted)

 

 

 

S1P Receptor Inhibitors Related Products:

Fingolimod hydrochloride; JTE-013; Ozanimod

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Friendly link:

Copyright Copyright (C) 2018-2024 Taizhou Crene Biotechnology Co.,Ltd.  

Address:Economic Developed Zone of Taizhou Zhejiang China