S-6472 Cefaclor

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Chemical Information

Product name：S-6472 Cefaclor	Purity：98% min
CAS NO：53994-73-3	Solubility：DMSO : 18.5 mg/mL (50.30 mM)
Molecular Formula：C₁₅H₁₄ClN₃O₄S	Package：Package according to customer requirements
Molecular Weight：367.807	Storage：Store at -20℃

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Remarks

Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic that inhibits cell wall synthesis. The antibiotic is active against a wide spectrum of common pathogens, including gram-positive and gram-negative bacteria. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

Properties:

Appearance & Physical State: white crystalline solid

Density: 1.62g/cm3

Boiling Point: 713.4ºC at 760mmHg

Flash Point: 385.2ºC

Refractive Index: 1.705

Antibiotics Inhibitors Related Products:

Idarubicin HCl; Fumagillin; Brefeldin A

References

[1]. King BA, et al. Adverse skin and joint reactions associated with oral antibiotics in children: the role of cefaclor in serum sickness-like reactions. J Paediatr Child Health. 2003 Dec;39(9):677-81.

[2]. Ito S, et al. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993 May;168(5):1393-9.