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Product :

WZ811

WZ811 55778-02-4
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Chemical Information
Product name:WZ811 Purity:98% min
CAS NO:55778-02-4 Solubility:DMSO : 10 mg/mL (34.44 mM)
Molecular Formula:C18H18N4 Package:Package according to customer requirements
Molecular Weight:290.362 Storage:Store at -20℃
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Remarks

WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist. WZ811 shows subnanomolar potency (EC50 = 0.3 nM) in an affinity binding assay. In addition, when subjected to in vitro functional evaluation, WZ811 efficiently inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cyclic adenosine monophophate (cAMP) levels (EC50 = 1.2 nM) and SDF-1 induced Matrigel invasion (EC50 = 5.2 nM). The chemical structure of WZ811 is very similar to that of MSX-122.

 

 

 

CXCR Inhibitors Related Products:

Plerixafor (AMD3100); Plerixafor 8HCl; Navarixin; AMD 3465 hexahydrobromide; LIT-927

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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