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Product :

Clozapine

Clozapine 5786-21-0
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Chemical Information
Product name:Clozapine Purity:98% min
CAS NO:5786-21-0 Solubility:Soluble in DMSO, not in water
Molecular Formula:C18H19ClN4 Package:Package according to customer requirements.
Molecular Weight:326.823 Storage:Store at -20℃
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Remarks

Clozapine is an atypical antipsychotic drug because it binds to serotonin as well as dopamine receptors. Clozapine is a partial agonist at the 5-HT1A subunit of the serotonin receptor, putatively improving depression, anxiety, and the negative cognitive symptoms associated with schizophrenia. A direct interaction of clozapine with the GABAB receptor has also been shown. GABAB receptor-deficient mice exhibit increased extracellular dopamine levels and altered locomotor behaviour equivalent to that in schizophrenia animal models.

 

Properties:

Appearance & Physical State: a yellow, crystalline powder, very slightly soluble in water

Density: 1.31 g/cm3

Boiling Point: 477.8ºC at 760 mmHg

Melting Point: 182-185ºC

Flash Point: 242.8ºC

Refractive Index: 1.681

Stability: Stable at normal temperatures and pressures.

 

 

 

5-HT Receptor Inhibitors Related Products:

Iloperidone; Olanzapine; Agomelatine; Duloxetine hydrochloride; Duloxetine; Alosetron hydrochloride; Palonosetron hydrochloride; Lurasidone; Lurasidone hydrochloride; Ramosetron Hydrochloride; Atomoxetine hcl

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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