VX-702

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：VX-702	Purity：98% min
CAS NO：745833-23-2	Solubility：DMSO : ≥ 42 mg/mL (103.88 mM)
Molecular Formula：C₁₉H₁₂F₄N₄O₂	Package：Package according to customer requirements
Molecular Weight：404.318	Storage：Store at -20℃

Quality control

Remarks

VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. VX-702 prevents activation of p38MAPK and decrements in many platelet storage parameters after exposure to 16 °C without agitation for 24 h.

p38 MAPK Inhibitors Related Products:

SB203580; Doramapimod; SB-202190; PH-797804; Neflamapimod; TAK-715; R1487 HCl; SB239063; Losmapimod; Ralimetinib dimesylate

References

[1]. Kuliopulos A, et al. Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation. Thromb Haemost, 2004, 92(6), 1387-1393.

[2]. Braddock M, IDDB Meeting Report, 2005, March 14-15.

[3]. Gill A, IDDB Meeing Report, 2002, March 06-08.