JNJ303

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：JNJ303	Purity：99% min
CAS NO：878489-28-2	Solubility：DMSO : 62.5 mg/mL (141.73 mM)
Molecular Formula：C₂₁H₂₉ClN₂O₄S	Package：Package according to customer requirements
Molecular Weight：440.984	Storage：Store at +4°C

Quality control

COA

Remarks

JNJ 303 is a potent blocker of the voltage dependent IKs-channel encoded by KCNQ1/KCNE1 with IC50 of 64 nM. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).

Chemical Name:

2-(4-chlorophenoxy)-N-[(1R,3S)-5-(methanesulfonamido)-2-adamantyl]-2-methylpropanamide

Potassium Channel Inhibitors Related Prodcuts:

Glimepiride; Vonoprazan Fumarate; Gliclazide; Almitrine dimesylate; Dofetilide; Dronedarone HCl; Mitiglinide Calcium ; Glyburide

References

[1]. Julie Albrecht, et al. The effect of the KV7/KCNE 1 inhibitor JNJ 303 on heart slices and the L-type calcium channel of cardiac cells.