Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
Properties:
Density: 1.438 g/cm3
Boiling Point: 729.134ºC at 760 mmHg
Flash Point: 394.766ºC
Related Products:
SRT1720 hcl; Barasertib; ABT-751; MK-5108; SNS-314; SNS-314 mesylate; Abexinostat; Romidepsin; R547; Tubastatin A HCL; SCH900776; PF00477736; GW7647; Dalcetrapib