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RoMidepsin

RoMidepsin 128517-07-7
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Chemical Information
Product name:RoMidepsin Purity:98% min
CAS NO:128517-07-7 Solubility:DMSO : 50 mg/mL (92.47 mM)
Molecular Formula:C24H36N4O6S2 Package:Package according to customer requirements
Molecular Weight:540.696 Storage:Store at -20℃
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Remarks

Romidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia-induced angiogenesis and depletes several heat shock protein 90 (Hsp90)-dependent oncoproteins.

 

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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