Quetiapine fumarate

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Chemical Information

Product name：Quetiapine fumarate	Purity：99% min
CAS NO：111974-72-2	Solubility：DMSO : 50 mg/mL (113.24 mM)
Molecular Formula：C₄₆H₅₄N₆O₈S₂	Package：Package according to customer requirements
Molecular Weight：883.086	Storage：Store at -20℃

Quality control

Remarks

Quetiapine Fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.

Properties:
Appearance & Physical State: white crystalline solid
Melting Point: 174-176ºC
Boiling Point: 556.5ºC at 760 mmHg
Flash Point: 290.4ºC
Vapor Pressure: 3.22E-13mmHg at 25°C

Dopamine Receptor Inhibitors Related Products:

Ropinirole hydrochloride; Domperidone; Paliperidone; Amisulpride; ONC206; Sulpiride; SKF-38393 HCl

References

[1]. Sheehan DV, Locklear J, Sveds?ter H, Datto C. Long-term functioning and sleep quality in patients with major depressive disorder treated with extended-release quetiapine fumarate. Int Clin Psychopharmacol. 2012 Sep;27(5):239-48.

[2]. Endicott J, Sveds?ter H, Locklear JC. Effects of once-daily extended release quetiapine fumarate on patient-reported outcomes in patients with generalized anxiety disorder. Neuropsychiatr Dis Treat. 2012;8:301-311.