Ropinirole hydrochloride

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Chemical Information

Product name：Ropinirole hydrochloride	Purity：99% min
CAS NO：91374-20-8	Solubility：DMSO : 17 mg/mL (57.27 mM)
Molecular Formula：C₁₆H₂₅ClN₂O	Package：Package according to customer requirements
Molecular Weight：296.836	Storage：Store at -20℃

Quality control

Remarks

Ropinirole hydrochloride is a potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease.

Properties:
Appearance & Physical State: off-white solid
Boiling Point: 410.5ºC at 760mmHg
Melting Point: 241-243ºC

Dopamine Receptor Inhibitors Related Products:

Quetiapine fumarate; Domperidone; Paliperidone; Amisulpride; ONC206; Sulpiride; SKF-38393 HCl

References

[1]. Eden, R.J., et al., Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonist. Pharmacol Biochem Behav, 1991. 38(1): p. 147-54.

[2]. Iida, M., et al., Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist. Brain Res, 1999. 838(1-2): p. 51-9.