MRT67307 is a potent ULK inhibitor and SIK inhibitor. MRT67307 potently inhibits ULK1 and ULK2 in vitro and block autophagy in cells. ULK1 inhibition results in accumulation of stalled early autophagosomal structures, indicating a role for ULK1 in the maturation of autophagosomes as well as initiation.
IκB/IKK Inhibitors Related Products:
Resveratrol; BAY 11-7082; IKK-16; TPCA-1; BMS-345541; BMS-345541 HCl; SC-514; LY2409881 trihydrochloride; IMD-0354; Bardoxolone methyl; TBK1; WS6; WS3