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IMD-0354 IKK2 Inhibitor V

IMD-0354 IKK2 Inhibitor V 978-62-1
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Chemical Information
Product name:IMD-0354 IKK2 Inhibitor V Purity:98% min
CAS NO:978-62-1 Solubility:DMSO : ≥ 100 mg/mL (260.64 mM)
Molecular Formula:C15H8ClF6NO2 Package:Package according to customer requirements
Molecular Weight:383.673 Storage:Store at -20℃
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COA
Remarks

IMD-0354 is a nuclear factor-kappaB (NF-κB) activation inhibitor potentially for the treatment of atopic dermatitis. IMD-0354 significantly reduces the accumulation of inflammation damage and oxidative lesions. Furthermore, IMD-0354 treatment could block IκBα degradation and suppress mRNA and protein level of nuclear factor (NF) -κB p65. IMD-0354. IMD-0354 exerts anti-asthmatic action, at least partially, by blocking the activation and clonal expansion of CD4(+) Teff cells in the MLNs, which, consequently, prevents infiltration of the lungs with activated CD4(+) Teff cells.

 

 

 

IκB/IKK Inhibitors Related Products:

Resveratrol; BAY 11-7082; IKK-16; TPCA-1; BMS-345541; BMS-345541 HCl; SC-514; LY2409881 trihydrochloride; Bardoxolone methyl; TBK1; WS6; WS3; MRT67307

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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