CA-5f

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Chemical Information

Product name：CA-5f	Purity：98% min
CAS NO：1370032-19-1	Solubility：DMSO : 77.5 mg/mL (199.51 mM)
Molecular Formula：C₂₄H₂₄N₂O₃	Package：Package according to customer requirements
Molecular Weight：388.459	Storage：Store at -20℃

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Remarks

CA-5f is a potent late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer. CA-5f exhibited strong cytotoxicity against A549 non-small cell lung cancer (NSCLC) cells. CA-5f effectively suppressed the growth of A549 lung cancer xenograft as a single agent with an excellent tolerance in vivo.

Autophagy Inhibitors Related Products:

SBI-0206965; PFK-015; GSK690693; DC661; IITZ-01; ROC-325

References

[1]. Zhang L, et al. Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer. Autophagy. 2019 Mar;15(3):391-406.