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GSK690693

GSK690693 937174-76-0
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Chemical Information
Product name:GSK690693 Purity:98% min
CAS NO:937174-76-0 Solubility:10 mM in DMSO
Molecular Formula:C21H27N7O3 Package:Package according to customer requirements
Molecular Weight:425.484 Storage:Store at -20℃
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Remarks
GSK690693 is a pan-AKT kinase inhibitor, is also a n aminofurazan-derived inhibitor of Akt kinases with potential antineoplastic activity. Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, which may result in the inhibition of protein phosphorylation events downstream from Akt kinases in the PI3K/Akt signaling pathway, and, subsequently, the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. In addition, this agent may inhibit other protein kinases including protein kinase C (PKC) and protein kinase A (PKA). As serine/threonine protein kinases which are involved in a number of biological processes, AKT kinases promote cell survival by inhibiting apoptosis and are required for glucose transport. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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