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Miltefosine

Miltefosine 58066-85-6
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Chemical Information
Product name:Miltefosine Purity:98% min
CAS NO:58066-85-6 Solubility:DMSO : 5 mg/mL (12.27 mM)
Molecular Formula:C21H46NO4P Package:Package according to customer requirements
Molecular Weight:407.568 Storage:Store at -20℃
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Remarks

Miltefosine is an orally- and topically-active alkyl-phosphocholine compound with potential antineoplastic activity. Miltefosine targets cellular membranes, modulating cell membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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