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AZD5363 Capivasertib

AZD5363 Capivasertib 1143532-39-1
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Chemical Information
Product name:AZD5363 Capivasertib Purity:98% min
CAS NO:1143532-39-1 Solubility:DMSO : ≥ 21.5 mg/mL (50.13 mM)
Molecular Formula:C21H25ClN6O2 Package:Package according to customer requirements
Molecular Weight:428.915 Storage:Storage:Store at -20℃
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Remarks

AZD5363, also known as Capivasertib, is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AKT inhibitor AZD5363 binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism. A wide range of solid and hematological malignancies show dysregulated PI3K/AKT/mTOR signaling due to mutations in multiple signaling components.


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