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SC66

SC66 871361-88-5
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Chemical Information
Product name:SC66 Purity:98% min
CAS NO:871361-88-5 Solubility:DMSO : ≥ 34 mg/mL (123.04 mM)
Molecular Formula:C18H16N2O Package:Package according to customer requirements
Molecular Weight:276.332 Storage:Store at -20℃
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Remarks

SC66 is a novel and potent AKT inhibitor, which reduced cell viability in a dose- and time-dependent manner, inhibited colony formation and induced apoptosis in HCC cells. SC66 treatment led to a reduction in total and phospho-AKT levels. SC66 significantly potentiated the effects of both conventional chemotherapeutic and targeted agents, doxorubicin and everolimus, respectively. In vivo, SC66 inhibited tumor growth of Hep3B cells in xenograft models, with a similar mechanism observed in the in vitro model. SC66 had antitumor effects on HCC cells.

 

 

 

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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