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CCT128930

CCT128930 885499-61-6
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Chemical Information
Product name:CCT128930 Purity:98% min
CAS NO:885499-61-6 Solubility:10 mM in DMSO
Molecular Formula:C18H20ClN5 Package:Package according to customer requirements
Molecular Weight:341.838 Storage:Store at -20℃
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Remarks

CCT128930 is a novel ATP-competitive AKT inhibitor discovered using fragment- and structure-based approaches. It is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference. CCT128930 exhibited marked antiproliferative activity and inhibited the phosphorylation of a range of AKT substrates in multiple tumor cell lines in vitro, consistent with AKT inhibition.

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