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Akti-1/2 AKT inhibitor VIII

Akti-1/2 AKT inhibitor VIII 612847-09-3
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Chemical Information
Product name:Akti-1/2 AKT inhibitor VIII Purity:98% min
CAS NO:612847-09-3 Solubility:DMSO : 20 mg/mL (36.26 mM); H2O : < 0.1 mg/mL
Molecular Formula:C34H29N7O Package:Package according to customer requirements
Molecular Weight:551.64 Storage:Store at -20℃
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AKT inhibitor VIII, also known as AKTi-1/2, is a potent, selective and ell permeable, allosteric inhibitor of Akt 1 and 2, which efficiently inhibits CaMKIα activity and aryl hydrocarbon receptor pathway. AKT inhibitor VIII suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells. AKT inhibitor VIII displays good selectivity against a panel of 70 other kinases with micromolar inhibition against some kinases, for example, calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase.




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