PFK-015

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Chemical Information

Product name：PFK-015	Purity：98% min
CAS NO：4382-63-2	Solubility：DMSO : 25.2 mg/mL (96.82 mM)
Molecular Formula：C₁₇H₁₂N₂O	Package：Package according to customer requirements
Molecular Weight：260.29	Storage：-20℃

Quality control

Remarks

PFK-015 is an effective inhibitor of PFKFB3 with IC50 of 110 nM (recombinant PFKFB3) and inhibits PFKFB3 activity in cancer cells with IC50 of 20 nM.

Autophagy Inhibitors Related Products:

SBI-0206965; GSK690693; DC661; IITZ-01; ROC-325; CA-5f

References

[1]. Pfkfb3 inhibitor and methods of use as an anti-cancer therapeutic

[2]. Brian Clem, et al. Abstract 2825: Characterization of a novel small molecule antagonist of 6-phosphofructo-2-kinase that suppresses glucose metabolism and tumor growth. Cancer Research: April 15, 2011; Volume 71, Issue 8, Supplement 1