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SB 271046 HCL

SB 271046 HCL 209481-24-3
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Chemical Information
Product name:SB 271046 HCL Purity:98% min
CAS NO:209481-24-3 Solubility:10 mM in DMSO
Molecular Formula:C20H23Cl2N3O3S2 Package:Package according to customer requirements
Molecular Weight:488.442 Storage:Store at -20℃
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SB-271046 is one of the first selective 5-HT6 receptor antagonists to be discovered. SB-271046 was found to be potent and selective in vitro and had good oral bioavailability in vivo, but had poor penetration across the blood–brain barrier. SB-271046 was found to increase levels of the excitatory amino acid neurotransmitters glutamate and aspartate, as well as dopamine and noradrenaline in the frontal cortex and hippocampus of rats, and 5-HT6 antagonists have been shown to produce nootropic effects in a variety of animal studies. Suggested applications of these drugs include treatment of schizophrenia and other psychiatric disorders.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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