Benfotiamine

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Chemical Information

Product name：Benfotiamine	Purity：98% min
CAS NO：22457-89-2	Solubility：DMSO : ≥ 50 mg/mL (107.19 mM)
Molecular Formula：C₁₉H₂₃N₄O₆PS	Package：Package according to customer requirements
Molecular Weight：466.4480	Storage：Store at 2-8°C

Quality control

Remarks

Benfotiamine, or S-benzoylthiamine O-monophosphate, is a synthetic S-acyl derivative of thiamine (vitamin B1). It is prescribed there for treating sciatica and other painful nerve conditions. It is marketed as a medicine and/or dietary supplement, depending on the respective Regulatory Authority. Benfotiamine upregulates antioxidative system in activated BV-2 microglia cells. Benfotiamine enhances antioxidant defenses and protects against cisplatin-induced DNA damage in nephrotoxic rats.

Properties:
Appearance & Physical State: shinning black powder
Density: 1.444 g/cm3
Melting Point: 165ºC
Boiling Point: 745.1ºC at 760 mmHg
Flash Point: 404.4ºC
Refractive Index: 1.645
Storage Condition: 2-8ºC
Vapor Pressure: 2.55E-23mmHg at 25°C

NF-κB Inhibitors Related Products:

Bortezomib; Bortezomib pinanediol ester; TPCA-1; Bardoxolone methyl; Curcumin; QNZ (EVP4593); Triptolide; JSH-23; Benfotiamine; Omaveloxolone; Erdosteine

References

[1]. Tarallo S, Beltramo E, Berrone E, Porta M. Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment. Acta Diabetol. 2012 Dec;49 Suppl 1:141-51.

[2]. Engelen L, Stehouwer CD, Schalkwijk CG. Current therapeutic interventions in the glycation pathway:Evidence from clinical studies. Diabetes Obes Metab. 2012 Dec 26.