Chloramphenicol

Chloramphenicol is a bacteriostatic antibiotic that inhibits bacterial protein synthesis. It is usually bacteristatic and effective against a wide range of gram-positive and gram-negative organisms. Chloramphenicol is used as a selection agent for transformed cells containing chloramphenicol resistance genes. Chloramphenicol exhibits anti-rickettsial activity and is also active against chlamydias of the psittacosis-lymphogranuloma group.

Properties:
Appearance & Physical State: white to off-white crystalline powder
Density: 1.547 g/cm3
Boiling Point: 644.9ºC at 760 mmHg
Melting Point: 149-153ºC
Flash Point: 343.8ºC
Refractive Index: 20 ° (C=5, EtOH)
Water Solubility: 2.5 g/L (25 º C)

Bacterial inhibitor Related Products:

Pretomanid; Pyrazinamide; Sulfanilamide; Daptomycin; Tigecycline; Rifabutin; Biapenem; Teicoplanin; Cefdinir; Azithromycin; Trimethoprim; Amoxicillin; Dalbavancin; Ceftibuten dihydrate; Besifloxacin; Solithromycin; Cefditoren; Dalbavancin HCl; Cefoxitin Sodium; Besifloxacin Hydrochloride; Cefditoren Pivoxil; Cefoxitin acid; Walrycin B; Vancomycin HCl

[1]. Jardetzky, O., Studies on the mechanism of action of chloramphenicol. I. The conformation of chlioramphenicol in solution. J Biol Chem, 1963. 238: p. 2498-508.

[2]. Wolfe, A.D. and F.E. Hahn, Mode of Action of Chloramphenicol. Ix. Effects of Chloramphenicol Upon a Ribosomal Amino Acid Polymerization System and Its Binding to Bacterial Ribosome. Biochim Biophys Acta, 1965. 95: p. 146-55.