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Product :

FK866 Daporinad

FK866 Daporinad  658084-64-1
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Chemical Information
Product name:FK866 Daporinad Purity:98% min
CAS NO:658084-64-1 Solubility:DMSO : ≥ 50 mg/mL (127.71 mM)
Molecular Formula:C24H29N3O2 Package:Package according to customer requirements
Molecular Weight:391.506 Storage:Store at -20℃
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COA
Remarks

Daporinad, also known as APO-866 and FK866, is a small molecule with potential antineoplastic and antiangiogenic activities. NMPRTase inhibitor APO866 binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from niacinamide (vitamin B3), which may deplete energy reserves in metabolically active tumor cells and induce tumor cell apoptosis. In addition, this agent may inhibit tumor cell prioduction of vascular endothelial growth factor (VEGF), resulting in the inhibition of tumor angiogenesis.

 


 

Transferase Inhibitors Related Products:

Tipifarnib; Lonafarnib; A922500; OSMI-1; PF-04620110; Ezatiostat; PF-9366

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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