Nicousamide Pyrotinib Maleate

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Chemical Information

Product name：Nicousamide Pyrotinib Maleate	Purity：98% min
CAS NO：704881-43-6	Solubility：Soluble in DMSO
Molecular Formula：C₁₈H₁₂N₂O₉	Package：Package according to customer requirements.
Molecular Weight：400.29	Storage：-20 ℃

Quality control

Remarks

Nicousamide is a TGF-β inhibitor potentially for the treatment of renal insufficiency.

HER2 Inhibitors Related Products:

Tucatinib; Afatinib (BIBW2992) Dimaleate; Poziotinib; ARRY-380 analog; Trastuzumab; Canertinib; Lapatinib; Lapatinib ditosylate; Pyrotinib; Pyrotinib Maleate

References

1: Qi W, Zhao Q, Liu H, Jiang J, Chen X, Hu P. Determination of nicousamide in human plasma by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2013 Apr 15;77:158-62. doi: 10.1016/j.jpba.2013.01.025. Epub 2013 Jan 26. PubMed PMID: 23416370.

2: Zhang S, Li H, Li Y, Zhang F, Liu Y, Chen X. Nicousamide normalizes renovascular hypertension in two-kidney one-clip hypertensive rats. Biomed Rep. 2013 Jan;1(1):89-92. Epub 2012 Oct 22. PubMed PMID: 24648900; PubMed Central PMCID: PMC3956876.